Emodin

Description

Noksoul operates a GMP-, ISO- and HACCP-certified production base in the Hongjiang High-tech Zone of Hunan Province, specializing in Emodin, a high-purity natural anthraquinone isolated from the dried rhizome of Rheum palmatum (Chinese rhubarb) through controlled food-grade solvent extraction, column chromatography and recrystallization. Our production workflow isolates and standardizes emodin, the representative hydroxyanthraquinone active, delivering consistent ≥98% HPLC material for intestinal-health and detox supplement formulators, antibacterial and anti-inflammatory product developers, and pharmaceutical intermediate research teams worldwide.

Why Choose Noksoul Emodin

• Natural Anthraquinone Active.  Emodin (CAS 518-82-1) is a well-characterized hydroxyanthraquinone (1,3,8-trihydroxy-6-methyl-anthraquinone) with documented cathartic, antibacterial, anti-inflammatory and antioxidant activity. Sourced from rhubarb rhizome, it is delivered as a single standardized ≥98% active ingredient, simplifying dose design and label-claim compliance.
• Controlled Purification Preserving Anthraquinone Activity.  Manufacturing applies optimized food-grade solvent extraction, chromatographic separation and recrystallization under controlled conditions, preserving the anthraquinone chromophore and bioactivity while removing co-extracted sugars and unrelated impurities.
• HPLC-Driven Batch-to-Batch Standardization.  Every production lot is quantified by HPLC for emodin purity (≥98%), alongside profiling of related anthraquinones such as rhein, chrysophanol, physcion and aloe-emodin. Multi-analyte documentation gives formulators full traceability to support regulatory filing and label claims.
• Controlled Impurity and Residual Management.  Our quality system monitors potential cross-contact plant allergens. Each batch is tested for residual solvents in compliance with ICH Q3C guidelines, minimizing processing-related contaminants in the final crystalline powder.
• Heavy-Metal and Microbiological Compliance.  Each lot undergoes ICP-MS heavy-metal screening, full microbiological panel testing and critical safety parameter verification before commercial release, in line with our established ISO / GMP / HACCP quality system.
• Complete Export Documentation.  COA, MSDS, impurity profile certificate, heavy-metal test report and batch-traceability records accompany every shipment. With over two decades of industry expertise, our materials serve customers across Europe, the Americas, Southeast Asia, Japan and South Korea.

What Is Emodin

Botanical Source and Biological Composition

Emodin (CAS 518-82-1, C15H10O5, MW 270.24 g/mol) is the representative hydroxyanthraquinone naturally accumulated in the dried rhizome of Rheum palmatum (Chinese rhubarb) and related Polygonum species (P. cuspidatum, P. multiflorum). As a traditional anthraquinone cathartic, it supports intestinal motility and bowel evacuation. It also exhibits documented antibacterial, anti-inflammatory and antioxidant activity, and is widely studied in pharmacology for its multi-mode biological effects. These properties underpin its use in intestinal-health and detox supplements, antibacterial and anti-inflammatory formulations, and pharmaceutical intermediate research.

Standardized Emodin vs. Crude Rhubarb Root Powder

Crude rhubarb rhizome powder contains emodin alongside other anthraquinones (rhein, chrysophanol, physcion, aloe-emodin), tannins, polysaccharides and fibre; emodin content varies widely with rhubarb species, growing region, harvest time and processing. Standardized emodin produced via extraction, chromatography and recrystallization is highly enriched to ≥98% by HPLC, enabling precise dose control and reliable batch-to-batch reproducibility for finished products.

Production Process

Incoming Rheum palmatum rhizome raw material is inspected for botanical identity, initial emodin content, heavy-metal levels and microbiological status prior to manufacturing.

• Raw-Material Pretreatment — Dried rhubarb rhizome is cleaned, crushed and screened to remove foreign plant fragments and physical contaminants; botanical identity is confirmed before extraction.
• Food-Grade Solvent Extraction — Pretreated material undergoes circulating food-grade solvent extraction under controlled conditions to solubilize anthraquinone components, maximizing emodin yield while limiting co-extraction of tannins and polysaccharides.
• Concentration and Crude Enrichment — The extraction liquor is concentrated to recover solvent and obtain an enriched crude anthraquinone fraction.
• Column Chromatography Purification — Crude concentrate is loaded onto chromatographic resin for selective adsorption and elution, separating emodin from other co-extracted anthraquinones and impurities.
• Recrystallization for Final Standardization — Chromatography-purified emodin solution is subjected to controlled recrystallization to achieve the target ≥98% HPLC purity; orange crystalline solids are isolated by filtration.
• Quality Release and Packaging — Dried powder is assayed for emodin content by HPLC, residual solvents, related-substance profile, heavy metals, moisture and microbiological safety. Qualified material is packed into double-layer PE inner bags with desiccants, then sealed within light-proof, moisture-barrier fibre drums.

Functional Properties & Benefits

• Intestinal Motility and Bowel Support.  As a classic anthraquinone cathartic, emodin is traditionally used in intestinal-health and occasional bowel-support formulations.
• Antibacterial and Anti-Inflammatory Activity.  Documented antibacterial and anti-inflammatory effects support products positioned for gut comfort and topical anti-bacterial use.
• Antioxidant Activity.  Hydroxyanthraquinone antioxidant activity supports cellular defence against oxidative stress.
• Hepatic and Metabolic Research.  Emodin is widely studied in pharmacology for liver, metabolic and inflammation-related mechanisms, making it a valuable research-grade active.
• Pharmaceutical Intermediate.  The defined anthraquinone structure makes high-purity emodin a reference compound for natural-product chemistry and pharmaceutical intermediate development.

Applications

• Intestinal-Health and Occasional Bowel-Support Supplements.  Supplied for hard capsules, tablets and sachet formats. ≥98% HPLC purity and full regulatory documentation support intestinal comfort and occasional bowel-movement supplement positioning.
• Antibacterial and Anti-Inflammatory Formulations.  Used in gut-comfort and topical anti-bacterial formulations, often combined with other botanicals.
• Pharmaceutical Intermediates and Scientific Research.  ≥98% HPLC-grade emodin supplied for in-vitro and in-vivo pharmacological research, natural-product chemistry and pharmaceutical intermediate R&D.

Contact Noksoul for Emodin Supply

Noksoul supplies emodin with HPLC-validated ≥98% purity profiles, backed by comprehensive third-party testing and an established ISO / GMP / HACCP quality system. Flexible order sizes are available from laboratory-scale samples to full-container bulk shipments. Custom-purity grades, particle-size specifications and full documentation can be provided on request.

Shipping Method

We offer flexible, reliable shipping options to meet your delivery needs, including:

• Air freight & Sea freight
• International courier services: FedEx, DHL, PostNL, EMS, UPS
• Regional express services: SF Express

 

We will match the most suitable shipping method according to your order volume, delivery address, and urgency, to ensure your goods reach you safely and on schedule.Our Packaging

We offer a range of professional packaging options tailored to different order sizes:

• 1kg per aluminum bag
• 5-10kg per carton
• 25kg per drum

 
For products with special transportation requirements, we provide customized, enhanced packaging solutions. Take Deoxyarbutin as an example: as this ingredient may discolor during transit, we use vacuum-sealed packaging to preserve its quality and appearance.

Our Factory

As a professional plant extract supplier, we implement stringent quality control across every single step of our factory's operations:

• Raw Material Stage: We exercise strict oversight over the planting of raw materials, as well as the sourcing and purchasing processes
• Production Stage: Every detail of the product manufacturing process is standardized and monitored
• Final Stage: We also carry out strict checks for the product packaging procedure

This full-chain quality control ensures that every product we deliver meets the highest standards of quality.