Naringin

Description

Noksoul operates a GMP-, ISO- and HACCP-certified production base in the Hongjiang High-tech Zone of Hunan Province, specializing in Naringin, a high-purity natural flavanone glycoside isolated from citrus peel (pomelo Citrus grandis and grapefruit Citrus paradisi) through controlled food-grade solvent extraction, column chromatography and recrystallization. Our production workflow isolates and standardizes naringin, the principal bitter citrus flavanone glycoside, delivering consistent ≥98% HPLC material for liver-support and lipid-health supplement formulators, bitter-flavor and functional-beverage developers, and anti-aging / photoprotective cosmetic customers worldwide.

Why Choose Noksoul Naringin

• Natural Citrus Flavanone Glycoside.  Naringin (CAS 10236-47-2) is the principal bitter flavanone glycoside of citrus, composed of the aglycone naringenin linked to a neohesperidose disaccharide. It has documented antioxidant, hepatoprotective, lipid-modulating and anti-inflammatory activity, and is delivered as a single standardized ≥98% active ingredient, simplifying dose design and label-claim compliance.
• Controlled Purification Preserving Glycoside Activity.  Manufacturing applies optimized food-grade solvent extraction, chromatographic separation and recrystallization under controlled conditions, preserving the flavanone glycoside structure while removing co-extracted pectin, fibre and unrelated impurities.
• HPLC-Driven Batch-to-Batch Standardization.  Every production lot is quantified by HPLC for naringin purity (≥98%), alongside profiling of related citrus flavanone impurities such as hesperidin and eriocitrin. Multi-analyte documentation gives formulators full traceability to support regulatory filing and label claims.
• Controlled Impurity and Residual Management.  Our quality system monitors potential cross-contact plant allergens. Each batch is tested for residual solvents in compliance with ICH Q3C guidelines, minimizing processing-related contaminants in the final crystalline powder.
• Heavy-Metal and Microbiological Compliance.  Each lot undergoes ICP-MS heavy-metal screening, full microbiological panel testing and critical safety parameter verification before commercial release, in line with our established ISO / GMP / HACCP quality system.
• Complete Export Documentation.  COA, MSDS, impurity profile certificate, heavy-metal test report and batch-traceability records accompany every shipment. With over two decades of industry expertise, our materials serve customers across Europe, the Americas, Southeast Asia, Japan and South Korea.

What Is Naringin

Botanical Source and Biological Composition

Naringin (CAS 10236-47-2, C27H32O14, MW 580.53 g/mol) is the characteristic bitter flavanone glycoside accumulated in the outer peel of pomelo (Citrus grandis) and grapefruit (Citrus paradisi). Chemically it consists of the aglycone naringenin (4',5,7-trihydroxyflavanone) linked to a neohesperidose disaccharide. As a citrus bioflavonoid, naringin exhibits potent free-radical-scavenging antioxidant activity, hepatoprotective activity, lipid-modulating (cholesterol and triglyceride supporting) activity, and documented anti-inflammatory effects. It is also the well-known precursor of naringin dihydrochalcone, an intense sweetener. These multi-mode properties underpin its use in liver-support, lipid-health and antioxidant nutraceuticals, bitter-flavor functional beverages, and anti-aging / photoprotective cosmetics.

Standardized Naringin vs. Crude Citrus Peel Powder

Crude citrus peel powder contains naringin alongside large amounts of pectin, fibre, essential oils and other flavonoids (hesperidin, eriocitrin); naringin content varies with fruit variety, maturity and origin. Standardized naringin produced via extraction, chromatography and recrystallization is highly enriched to ≥98% by HPLC, enabling precise dose control and reliable batch-to-batch reproducibility for finished supplement, beverage and cosmetic products.

Production Process

Incoming citrus peel raw material (pomelo / grapefruit) is inspected for botanical identity, initial flavanone-glycoside content, heavy-metal levels and microbiological status prior to manufacturing.

• Raw-Material Pretreatment — Dried citrus peel is cleaned, crushed and screened to remove foreign plant fragments and physical contaminants; botanical identity is confirmed before extraction.
• Food-Grade Solvent Extraction — Pretreated peel undergoes circulating food-grade solvent extraction under controlled moderate temperature to solubilize flavanone glycosides, maximizing naringin yield while limiting co-extraction of pectin and pigments.
• Concentration and Crude Enrichment — The extraction liquor is vacuum-concentrated at low temperature to recover solvent and obtain an enriched crude flavanone glycoside fraction.
• Column Chromatography Purification — Crude concentrate is loaded onto chromatographic resin for selective adsorption and elution, separating naringin from other co-extracted flavonoids, sugars and plant-derived impurities.
• Recrystallization for Final Standardization — Chromatography-purified naringin solution is subjected to controlled recrystallization to achieve the target ≥98% HPLC purity; crystalline solids are isolated by filtration.
• Quality Release and Packaging — Dried powder is assayed for naringin content by HPLC, residual solvents, related-substance profile, heavy metals, moisture and microbiological safety. Qualified material is packed into double-layer PE inner bags with desiccants, then sealed within light-proof, moisture-barrier fibre drums.

Functional Properties & Benefits

• Hepatoprotective and Liver-Support Activity.  Naringin is widely used in liver-support and liver-detox nutraceutical formulations, supporting hepatic antioxidant defence against oxidative stress.
• Lipid and Cholesterol Support.  Documented lipid-modulating activity supports cholesterol- and triglyceride-health supplement positioning, often combined with other botanical actives.
• Antioxidant Activity.  Powerful free-radical-scavenging antioxidant properties support cellular defence against oxidative stress in daily-health and antioxidant-complex products.
• Bitter-Flavor and Functional Beverage Ingredient.  The characteristic citrus bitter note supports digestive / bitter-functional beverage and flavoring applications; naringin is also the precursor of naringin dihydrochalcone sweetener.
• Anti-Aging and Photoprotective Beauty.  In topical skincare, naringin delivers antioxidant and UV-triggered oxidative-stress defence, making it a desirable active for mature-skin and anti-aging formulations.

Applications

• Liver-Support and Liver-Detox Supplements.  Supplied for hard capsules, tablets and sachet formats. ≥98% HPLC purity and full regulatory documentation support liver-protection and daily liver-care supplement positioning.
• Lipid- and Cholesterol-Health Nutraceuticals.  Used in cardiovascular-support and lipid-health supplement blends, often combined with plant sterols, red yeast rice or omega-3 ingredients.
• Bitter-Flavor and Functional Beverages.  High-purity naringin serves as a citrus bitter-flavor active for digestive / bitter-functional beverages and as a precursor material for naringin dihydrochalcone sweetener production.
• Anti-Aging and Photoprotective Cosmetics.  Serves as an antioxidant active raw material for topical anti-aging serums, creams and lotions focused on UV defence and mature-skin care.

Contact Noksoul for Naringin Supply

Noksoul supplies naringin with HPLC-validated ≥98% purity profiles, backed by comprehensive third-party testing and an established ISO / GMP / HACCP quality system. Flexible order sizes are available from laboratory-scale samples to full-container bulk shipments. Custom-purity grades, particle-size specifications and full documentation can be provided on request.

Shipping Method

We offer flexible, reliable shipping options to meet your delivery needs, including:

• Air freight & Sea freight
• International courier services: FedEx, DHL, PostNL, EMS, UPS
• Regional express services: SF Express

 

We will match the most suitable shipping method according to your order volume, delivery address, and urgency, to ensure your goods reach you safely and on schedule.Our Packaging

We offer a range of professional packaging options tailored to different order sizes:

• 1kg per aluminum bag
• 5-10kg per carton
• 25kg per drum

 
For products with special transportation requirements, we provide customized, enhanced packaging solutions. Take Deoxyarbutin as an example: as this ingredient may discolor during transit, we use vacuum-sealed packaging to preserve its quality and appearance.

Our Factory

As a professional plant extract supplier, we implement stringent quality control across every single step of our factory's operations:

• Raw Material Stage: We exercise strict oversight over the planting of raw materials, as well as the sourcing and purchasing processes
• Production Stage: Every detail of the product manufacturing process is standardized and monitored
• Final Stage: We also carry out strict checks for the product packaging procedure

This full-chain quality control ensures that every product we deliver meets the highest standards of quality.